Kiekvienais metais spalio antrąjį šeštadienį minima Pasaulinė organų donorystės ir transplantacijos diena. Šią dieną siekiama paskatinti žmones sutikti būti donorais ir taip išgelbėti kitų gyvybes.
1996 m. Lietuvos Respublikos sveikatos apsaugos ministerija įsteigė Nacionalinį organų transplantacijos biurą. 2000 metais Lietuvoje įsteigtas Valstybinis žmogaus audinių ir organų donorų bei recipientų registras, kuriame kaupiami duomenys apie asmenis, pareiškusius sutikimą ar nesutikimą, kad jų audiniai ir (ar) organai po jų mirties būtų paimti transplantacijai.
Kiekvienas žmogus, norintis tapti donoru, turi užpildyti Donoro kortelę. Pasirašyti sutikimą galima bet kurioje asmens sveikatos priežiūros įstaigoje (poliklinikoje, ligoninėje ir kt.) arba šeimos gydytojo kabinete, arba interneto svetainėje www.donoryste.eu.
Nemažai žmonių atsisako būti donorais dėl įvairių baimių, – kad kažkas gali būti suinteresuotas nužudyti dėl organų, kad tai prieštarauja religijai. Iš tiesų tokios baimės nepagrįstos. Informacija apie Donoro kortelės savininkus saugoma, vadovaujantis Lietuvos Respublikos teisės aktų nustatytais asmens duomenų apsaugos reikalavimais. Informacija apie Donoro kortelės savininką gali būti suteikiama tik jam pačiam arba gydytojui po Donoro kortelės savininko mirties.
Katalikų bažnyčia pritaria neatlygintinam mirusio žmogaus audinių ir organų dovanojimui kitam žmogui, kurį transplantacija gali išgelbėti nuo mirties. Katalikų nuomone, organų donorystė yra broliškos meilės auka. Transplantacija etiškai ir morališkai yra priimtina Vatikanui.
Organų donorystei pritaria ir daugybė kitų religijų – musulmonų, indų, graikų ortodoksų.
Organų donorystė Lietuvoje yra savanoriška ir neatlygintina, t. y. tuo neuždarbiaujama, o savo noru siekiama suteikti kitam žmogui galimybę išgyventi.
Lietuvoje per 2014 metų pirmą pusmetį buvo atliktos 68 transplantacijos, deja, laukiančiųjų savo donorų žymiai daugiau – 327 asmenys. Iki 2014 metų lapkričio 1 dienos Organų donoro kortelę įsigijo 20 009 asmenys.
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